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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KCNJ1 All Species: 25.76
Human Site: T191 Identified Species: 62.96
UniProt: P48048 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48048 NP_000211.1 391 44795 T191 R P K K R A K T I T F S K N A
Chimpanzee Pan troglodytes XP_522246 391 44791 T191 R P K K R A K T I T F S K N A
Rhesus Macaque Macaca mulatta XP_001113379 391 44839 T191 R P K K R A K T I T F S K N A
Dog Lupus familis XP_546403 479 54277 T279 R P K K R A K T I T F S K N A
Cat Felis silvestris
Mouse Mus musculus O88335 372 42757 R184 K N A V I S K R G G K L C L L
Rat Rattus norvegicus P35560 391 44945 T191 R P K K R A K T I T F S K N A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505779 453 51353 T253 R S K K C A K T I T F S K N A
Chicken Gallus gallus P52186 427 48500 T192 K P K K R N E T L V F S H N A
Frog Xenopus laevis NP_001087438 372 42205 R184 K N A V I S K R G G K L C L L
Zebra Danio Brachydanio rerio NP_001092204 375 42248 Q187 W K G N L C L Q I R V A N L R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 97.4 76.4 N.A. 88.2 91 N.A. 76.3 39.8 79.8 57.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.4 98.4 78.7 N.A. 91.3 94.6 N.A. 81.2 62.5 87.2 70 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 6.6 100 N.A. 86.6 60 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 20 100 N.A. 86.6 80 20 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 20 0 0 60 0 0 0 0 0 10 0 0 70 % A
% Cys: 0 0 0 0 10 10 0 0 0 0 0 0 20 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 70 0 0 0 0 % F
% Gly: 0 0 10 0 0 0 0 0 20 20 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % H
% Ile: 0 0 0 0 20 0 0 0 70 0 0 0 0 0 0 % I
% Lys: 30 10 70 70 0 0 80 0 0 0 20 0 60 0 0 % K
% Leu: 0 0 0 0 10 0 10 0 10 0 0 20 0 30 20 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 20 0 10 0 10 0 0 0 0 0 0 10 70 0 % N
% Pro: 0 60 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % Q
% Arg: 60 0 0 0 60 0 0 20 0 10 0 0 0 0 10 % R
% Ser: 0 10 0 0 0 20 0 0 0 0 0 70 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 70 0 60 0 0 0 0 0 % T
% Val: 0 0 0 20 0 0 0 0 0 10 10 0 0 0 0 % V
% Trp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _